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The TARGIT-A International Steering Committee, EBCC March 2010
The TARGIT-B Trial Steering Committee
Royal College of Surgeons, March 2014
2013 TARGIT-IORT users meeting, Mannheim
2014 TARGIT-IORT users meeting, Mannheim
2015 TARGIT-IORT users meeting, Mannheim
2016 TARGIT-IORT users meeting, USA
2016 TARGIT-IORT users meeting, Bangkok
2017 TARGIT Collaborative Group Conference
2017 TARGIT Collaborative Group Conference (USA)
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2018 TARGIT Collaborative Group Conference (USA)
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2019 TARGIT Collaborative Group Conference, USA (150 delegates)
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2020 TARGIT Collaborative Group Conference, USA (>200 delegates) (Just before the COVID-19 pandemic)
2022 (June) International Low-Energy X-Ray Irradiation Meeting, Frankfurt 
2022 (September) TARGIT Collaborative Group Conference, USA
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2023 (July) International Low-Energy X-Ray Irradiation Meeting, Frankfurt, 

This page is in the process of being populated and currently shows the specialist teams around London, UK 


Professor Jayant S Vaidya

Professor Jayant Vaidya is Professor of Surgery and Oncology at the University College London. His private practice is at the London Clinic and King Edward VII hospital, and St Johns and St Elizabeth hospital. He specialises in the diagnosis and treatment of benign diseases of the breast and breast cancer

He pioneered the concept and invented the surgical technique of targeted intraoperative radiotherapy (Intrabeam TARGIT IORT) along with Professor Michael Baum and Professor Tobias. They led the TARGIT-A randomised clinical trial to assess the clinical effectiveness of TARGIT IORT.

He has a busy clinical practice and has contributed extensively to the subject through his research, scientific papers, books and lectures.

Tel: Academic 0207 679 9280 | Clinical PA 07306 444 066, 0207 034 8890

Preferred method of contact is email: 

Mr Nathan Coombs

Mr Nathan Coombs is a senior consultant breast surgeon with 20 years experience.

Based at Swindon’s Great Western Hospital and the Shalbourne Suite, he first became involved in IORT in November 2012 and treated the first patient in Wiltshire in 2015. He graduated from Southampton University and has worked in the NHS since 1992.

He completed an 18 month fellowship at Sydney’s Breast Cancer Institute where he gained expertise in minimally invasive breast cancer techniques and researched extensively about hormone therapy and breast cancer risk.

Tel: 01793 646059 / 01793 646060

Professor Michael Douek

Michael Douek is Professor of Surgical Oncology and Breast Surgeon at King’s College London and Honorary Consultant Surgeon at Guy’s and St Thomas’ Hospital. He has a research interest in developing and evaluating novel techniques for cancer surgery. Besides developing a novel magnetic technique for sentinel node biopsy and lesion localization, he is one of the pioneers of intra-operative radiotherapy for breast cancer. He is currently Chief Investigator of a number of internationl clinical trials. In 2015, he was awarded a prestigious Hunterian Professorship by the Royal College of Surgeons of England.

Tel: Academic 020 7188 6380 | Clinical: 020 7188 1469

Ms Siobhan Laws​

Ms Siobhan Laws is Consultant Breast Surgeon at Royal Hampshire Hospitals NHS trust at Winchester and Basildon. She participated in the original TARGIT-A trial and currently recruiting patients in the TARGIT-B trial


TARGIT IORT Radiation Oncologists

Professor Jeffrey S Tobias

Professor Tobias is an internationally renowed consultant radiation oncologist, who along with Professor Michael Baum and Professor Vaidya pioneered the Intrabeam TARGIT IORT technique. Professor Tobias has published widely - scientific papers and books - on breast and other cancers.

He led the radiation oncology department at the University College London Hospital for over 35 years and now practices at UCLH and the London Clinic.

Dr Shiroma De Silva-Minor

Dr Shiroma De Silva-Minor is a consultant clinical oncologist, based at Oxford University Hospitals and the Great Western Hospital, Swindon.

Dr De Silva-Minor has expertise in the management of breast cancers (and prescribes both radiotherapy and chemotherapy). She has trained at nationally and internationally renowned cancer centres (including the Royal Marsden Hospital and Princess Margaret Hospital, Toronto, Canada) and has over 10 years of experience as a consultant.

UK Medical Physics and Clinical Teams

Medical physicists and radiographers operate the computer and machinery that allows the surgeons and radiation oncologists to deliver Intrabeam TARGIT IORT during the lumpectomy procedure.

These are the teams at the Great Western Hospital, Princess Alexandra Hospital and the London Clinic 

Team at the Great Western Hospital, Swindon led by Mr Nathan Coombs and Dr Shiroma De Silva-Minor
Team at the Princess Alexandra Hospital, Harlow, London, led by Mr Mr Ashraf Patel and Dr Julian Singer 
Team at the London Clinic include consultant surgeons Mr Gerald Gui, Mr Tim Davidson, Prof Jayant Vaidya, and Professor Jeffrey Tobias and others who are not in this photograph
Team at the Royal Hampshire County Hospital, Winchester 
Jayant S Vaidya
Jeffrey S Tobias
Michael Baum
They invented and clinically tested the Intrabeam TARGIT IORT procedure and performed the first case on 2 July 1998
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